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Also for NPPA (NM_006172)
|Peptide with sequence RIGAQSGLGCNSFR, from the C Terminus of the protein sequence according to NP_006163.1.|
|Test: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow
||Lot dependent; please refer to CoA along with shipment
||WB: 0.01-0.03ug/ml, IHC: 5-10ug/mL
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Homo sapiens natriuretic peptide A (NPPA)|
|ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; PND|
Entrez Gene 4878 Human
Entrez Gene 230899 Mouse
Entrez Gene 24602 Rat
Entrez Gene 608289 Dog
|The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq].|
|Secreted ProteinTransmembrane |
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TA309531 (0.01µg/ml) staining of Mouse Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Anti-NPPA antibody (5µg/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.