OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Recombinant Human Proteins All CACNB4 Proteins

CACNB4 (NM_000726) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP310440 Recombinant protein of human calcium channel, voltage-dependent, beta 4 subunit (CACNB4), transcript variant 2, 20 ug (Larger pack size?) 680
$398
In Stock
Add to Shopping Cart
spacer
Also for CACNB4 (NM_000726)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC210440. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:58 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Ion Channels: OtherDruggable Genome
Protein Pathways: MAPK signaling pathwayCardiac muscle contractionHypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Dilated cardiomyopathy
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000717 RefSeq Size: 3079 RefSeq ORF: 1563
LocusID: 785 Cytogenetic: 2q23.3  
Synonyms : CAB4; CACNLB4; EA5; EIG9; EJM; EJM4; EJM6
Summary: This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

bar
Inc 5000 Healthcare Company
View topsellers by:   Title | Price | Category | Popularity | Best Sellers Popular items by:   Popularity | Our Choices | All-Round Favorites | Title
View products by:   Title | Price | Category | Popularity | Best Sellers
Previous:  CACNB4 (NM_000726) Human cDNA ORF Clone - All CACNB4 ORF Clones - TrueORF - cDNA Clone : (GFP-tagged) - Human
Next:  CACNB4 (NM_001005746) Human cDNA Clone - CACNB4 Clone - TrueClone